Department of Anesthesiology

Department of Anesthesiology- Research Division

	Kevin K. Tremper, MD, PhD Chair of Anesthesiology Department Robert B. Sweet Professor Department of Anesthesiology Phone: 734-936-4235 Fax: 734-936-9091 Email: ktremper@umich.edu

While completing his Ph.D. in chemical engineering at the University of California at Berkeley, Dr. Tremper became interested in the applications of engineering to physiology and medicine. He conducted a short project involving a mathematical model of tissue perfusion and gas transport. At this point, Dr. Tremper decided to go to medical school to gain formal training in physiology and medicine. During medical school he worked on modeling of the oxygen transport to the heated skin surface, and was granted an early three-year graduation from medical school. Dr. Tremper then took a flexible internship at Harbor/UCLA Medical Center. During this internship he began experimental studies on oxygen and carbon dioxide measured noninvasively at the skin surface.

To complete the clinical aspect of this work Dr. Tremper remained at Harbor/UCLA Medical School for a year and a half after his internship as a research fellow in the surgical intensive care unit. During this time, he also became involved in perfluorochemical emulsions for oxygen transport and conducted the first clinical study in the United States with this "artificial blood" product in 1981.

In January of 1991, Dr. Tremper accepted the position of Professor and Chair of the Department of Anesthesiology at the University of Michigan. His main areas of research continue to be invasive and noninvasive monitoring of hemodynamics and oxygen transport. Clinically, Dr. Tremper has subspecialty interests in intensive care, cardiac anesthesia and anesthesia for head and neck surgery. He is a reviewer for 15 journals, a member of the editorial board for five, and am involved in the following national societies: Associate Examiner for the American Board of Anesthesiologists, Program Reviewer for the Accreditation Council for Graduate Medical Education, Past President of the Association of Anesthesiology Program Directors, and Member of the Educational Advisory Board for the Association of University Anesthesiologists.

Recent Publications:

Welch MB, Brummett CM, Welch TD, Tremper KK, Shanks AM, Guglani P, Mashour GA. Perioperative peripheral nerve injuries: a retrospective study of 380,680 cases during a 10-year period at a single institution. Anesthesiology. 2009 Sep; 111(3):490-7. [PubMed]

Kheterpal S, Martin L, Shanks AM, Tremper KK. Prediction and outcomes of impossible mask ventilation: a review of 50,000 anesthetics. Anesthesiology. 2009 Apr; 110(4):891-7. [PubMed]

Kheterpal S, Tremper KK, Heung M, Rosenberg AL, Englesbe M, Shanks AM, Campbell DA Jr. Development and validation of an acute kidney injury risk index for patients undergoing general surgery: results from a national data set. Anesthesiology. 2009 Mar; 110(3):505-15. [PubMed]

Nafiu OO, Bradin S, Tremper KK. Knowledge, attitude, and practice regarding cricoid pressure of ED personnel at a large U.S. teaching hospital. J Emerg Nurs. 2009 Feb; 35(1):11-5. [PubMed]

Mashour GA, Wang LY, Turner CR, Vandervest JC, Shanks A, Tremper KK. A retrospective study of intraoperative awareness with methodological implications. Anesth Analg. 2009 Feb; 108(2):521-6. [PubMed]

Nafiu OO, Kheterpal S, Morris M, Reynolds PI, Malviya S, Tremper KK. Incidence and risk factors for preincision hypotension in a noncardiac pediatric surgical population. Paediatr Anaesth. 2009 Mar; 19(3):232-9. [PubMed]

Kheterpal S, O'Reilly M, Englesbe MJ, Rosenberg AL, Shanks AM, Zhang L, Rothman ED, Campbell DA, Tremper KK. Preoperative and intraoperative predictors of cardiac adverse events after general, vascular, and urological surgery. Anesthesiology. 2009 Jan; 110(1):58-66. [PubMed]

Kheterpal S, Tremper KK, Shanks A, Morris M. Six-year follow-up on work force and finances of the United States anesthesiology training programs: 2000 to 2006. Anesth Analg. 2009 Jan; 108(1):263-72. [PubMed]

Kheterpal S, Khodaparast O, Shanks A, O'Reilly M, Tremper KK. Chronic angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy combined with diuretic therapy is associated with increased episodes of hypotension in noncardiac surgery. J Cardiothorac Vasc Anesth. 2008 Apr;22(2):180-6. [PubMed]

Nafiu OO, Reynolds PI, Bamgbade OA, Tremper KK, Welch K, Kasa-Vubu JZ. Childhood body mass index and perioperative complications. Paediatr Anaesth. 2007 May;17(5):426-30. [PubMed]

Tremper KK, Shanks A, Morris M.  Five-year follow-up on the work force and finances of United States anesthesiology training programs: 2000 to 2005.  Anesth Analg. 2007 Apr;104(4):863-8. [PubMed]

Kheterpal S, Gupta R, Blum JM, Tremper KK, O'Reilly M, Kazanjian PE. Electronic reminders improve procedure documentation compliance and professional fee reimbursement. Anesth Analg. 2007 Mar;104(3):592-7. [PubMed]

Rosenberg AL , Tremper KK. Wide variations in the cost-effectiveness of critical care. Crit Care Med. 2006 Nov;34(11):2849-51. [PubMed]

Kheterpal S, Han R, Tremper KK, Shanks A, Tait AR , O'Reilly M, Ludwig TA. Incidence and Predictors of Difficult and Impossible Mask Ventilation. Anesthesiology. 2006 Nov;105(5):885-891. [PubMed]

Blum JM, Kheterpal S, Tremper KK. A comparison of anesthesiology resident and faculty electronic evaluations before and after implementation of automated electronic reminders. J Clin Anesth. 2006 Jun;18(4):264-7. [PubMed]

Tremper KK, Shanks A, Morris M, Burnett DA. Validation of institutional support survey for anesthesiology training programs in the United States. Anesth Analg 102:644, 2006. [PubMed]

Tremper KK, Shanks A, Morris M. Trends in the financial status of United States anesthesiology training programs: 2000 to 2004. Anesth Analg 102:517-23, 2006. [PubMed]

Dorje P and Tremper K. Systolic pressure variation: a dynamic measure of the adequacy of intravascular volume. Seminars in Anesthesia, Perioperative Medicine and Pain 24: 147-53, 2005.

Tremper KK. Anesthesia information systems: developing the physiologic phenotype database. Anesth Analg 101: 620-1, 2005. [PubMed]

Puchakalaya MR and Tremper KK. Brown-Sequard Syndrome following removal of a cerebrospinal fluid drainage catheter after thoracic aortic syndrome. Anesth Analg 101: 322-324, 2005. [PubMed]

Tremper KK. As we move into the new millennium. Crit Care Med 33: 1647-1648, 2005. [PubMed]

Tremper KK. Hemoglobin-based oxygen carrying solutions: will they replace red blood cells? Anesth Analg 100:910-1, 2005. [PubMed]

Research Divisions