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Department of Anesthesiology

 

     

Department of Anesthesiology- Research Division

George A. Mashour, MD, PhD

Director, Division of Neuroanesthesiology

Assistant Professor of Anesthesiology & Neurosurgery

Faculty, Neuroscience Graduate Program

Faculty, Center for Sleep Science

Phone: 734-936-4280
Fax: 734-936-9091
Email:gmashour@umich.edu

 


Dr. Mashour received his M.D. and Ph.D in Neuroscience from Georgetown University and was awarded Fulbright Scholarships for neuroscience research at the Max Delbrück Center in Berlin , as well as the University of Bonn . He completed his internship, residency, and chief residency in anesthesiology at the Massachusetts General Hospital and Harvard Medical School , as well as fellowship training in neuroanesthesiology at the University of Michigan . His main clinical activities are neurosurgical anesthesia and neurocritical care.

Although Dr. Mashour’s doctoral and post-doctoral research focused on neuro-oncology, he has two current research interests: 1) the cognitive neuroscience of general anesthesia and related unconscious processes, and 2) the role of the cervical spine in airway evaluation and management.

1) Dr. Mashour is currently investigating the interfaces of sleep and general anesthesia, with a particular focus on REM activity and cognitive function. He is credited with developing the cognitive unbinding paradigm of general anesthesia, as well as advocating for the role of anesthesiology in the study of consciousness. Clinically, Dr. Mashour is studying awareness during general anesthesia. He is currently the principal investigator of a grant awarded by the ASA and FAER to investigate the BIS monitor in the prevention of awareness.

2) Dr. Mashour developed the “Extended Mallampati Score” as an alternative to the traditional Mallampati oropharyngeal classification and is currently exploring other predictive models for airway evaluation. Dr. Mashour is also investigating the effects of cervical spine limitation on airway management in the general surgical population, as well as in congenital disorders of the cervical spine such as Klippel-Feil Syndrome.

Selected Articles:

Mashour GA. Consciousness unbound: Toward a paradigm of general anesthesia. Anesthesiology 2004;100:428-433. (Published as a “Special Article”) [PubMed]

Mashour GA, Jiang YD, Osterman J. Perioperative treatment of patients with a history of intraoperative awareness and post-traumatic stress disorder. Anesthesiology 2006;104(4):893-4.

Mashour GA.
Integrating the science of consciousness and anesthesia. Anesthesia & Analgesia 2006;103:975-82.

Mashour GA
, Sandberg WS. Craniocervical extension improves specificity and predictive value of the Mallampati airway evaluation. Anesthesia & Analgesia 2006;103(5):1256-59.

Beltran S, Mashour GA. Unsuccessful cardiopulmonary resuscitation during neurosurgery: Is the supine position always optimal? Anesthesiology 2008; 108:163-64.

Mashour GA
, Stallmer M, Kheterpal S, Shanks A. Predictors of difficult intubation in patients with cervical spine limitations. Journal of Neurosurgical Anesthesiology 2008;20:110-115.

Mashour GA
. Toward a general theory of unconscious processes in psychoanalysis and anesthesiology. Journal of the American Psychoanalytic Association 2008;56(1):203-222.

Mashour GA
, Wang L, Turner CR, Shanks A, Vandervest JC, Tremper KK. A retrospective study of intraoperative awareness with methodological implications. In press, Anesthesia & Analgesia.

Selected Chapters:

Mashour GA , Szabo MD. Anesthesia for neurosurgery, in C linical Anesthesia Procedures of the Massachusetts General Hospital , 7 th edition, Editor: P Dunn, 2006, Lippincott-Williams, Chapter 24, pp. 441-463.

Forman SA, Mashour GA. Pharmacology of inhalational anesthetics, in Anesthesiology, 1 st edition, Editors: DE Longnecker, et al., 2007, McGraw-Hill, Chapter 37, pp. 739-766.

Mashour GA , Rosow C. Monitoring depth of anesthesia, in Handbook of Clinical Neurophysiology. Editor: M Nuwer, 2008, Elsevier, pp. 947-957.

Editorial Positions:

Guest Editor

- December 2006 issue of Seminars in Anesthesia, Perioperative Medicine and Pain, on the subject of “Consciousness and Anesthesiology"

- Fall 2008 issue of International Anesthesiology Clinics on the subject of “Unconscious Processes"

Ad Hoc Reviewer

Anesthesiology, Anesthesia & Analgesia, Journal of Cardiothoracic & Vascular Anesthesia, Journal of Clinical Anesthesia, Journal of Clinical Sleep Medicine, Nature Reviews Neuroscience, Neurochemical Research, Neurosurgery, Sleep

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