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George Mashour , M.D.
Director, Neuroanesthesiology

Dr. Mashour received his M.D. and Ph.D in Neuroscience from Georgetown University and was awarded Fulbright Scholarships for neuroscience research at the Max Delbrück Center in Berlin , as well as the University of Bonn . He completed his internship, residency, and chief residency in anesthesiology at the Massachusetts General Hospital and Harvard Medical School , as well as fellowship training in neuroanesthesiology at the University of Michigan . His main clinical activities are neurosurgical anesthesia and neurocritical care.
Although Dr. Mashour’s doctoral and post-doctoral research focused on neuro-oncology, he has two current research interests: 1) the cognitive neuroscience of general anesthesia and related unconscious processes, and 2) the role of the cervical spine in airway evaluation and management.
Dr. Mashour is currently investigating the interfaces of sleep and general anesthesia in association with Dr. Gina Poe , with a particular focus on REM activity and cognitive function. He is credited with developing the cognitive unbinding paradigm of general anesthesia, as well as advocating for the role of anesthesiology in the study of consciousness. Clinically, Dr. Mashour is studying awareness during general anesthesia and electroencephalographic techniques to prevent it. He is also currently editing a book on the subject of unconscious processes.
With his collaborator at the Massachusetts General Hospital , Dr. Mashour developed the “Extended Mallampati Score” as an alternative to the traditional Mallampati oropharyngeal classification. The Extended Mallampati Score was shown to be more predictive of difficult laryngoscopy in a pilot study, as well as a large validation study in the general surgical population at the University of Michigan . Dr. Mashour is also investigating the effects of cervical spine limitation on airway management in the general surgical population, as well as in congenital disorders of the cervical spine such as Klippel-Feil Syndrome.
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