Division of Anatomical Sciences Office of Medical Education

Don Lowell Fisher, Ph.D. Associate Professor of Anatomy 3767F Med Sci II (734) 763-3454 Email: (dlfisher@umich.edu) Community of Science Profile

To determine the feasibility of a teratogenic drug analysis using the postimplantation mouse embryo for in vitro cultivation with subsequent analysis of selective cytotoxicity or embryocidal effects. The long range goal is to determine the effects of an altered physical environment on developmental rate and quality during the postimplantation period of mammalian development, including alterations in the physical milieu, normal metabolites, exogenous chemicals, and irradiation.

Representative Publications:

1. Effects of hormones on postimplantation mouse embryos in vitro. II. Progesterone and estrogen, (with L. deVillarreol), Journal of Experimental Zoology, 224:205-210, 1982.
2. Cultured rat embryo accumulation of DNA, RNA and protein following maternal administration of sodium arsenate, Environmental Research, 28:1-9, 1982.
3. Your Remarkable Anatomy: An Overview for Health Professionals, Students and the General Public, Ann Arbor: Robbie Dean Press, 1997.

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