Stretch Mark Research

Frank Wang, MD, Gary Fisher, PhD, John Voorhees, MD, F.R.C.P.

Stretch marks are a very common problem. More than 50% of women are estimated to develop stretch marks during pregnancy. The pathophysiology underlying its formation is still unclear. A pilot study from our institution suggests that upregulation of procollagen I and III due to skin tension may play a role. Applying the methodologies in the above mentioned acne project, we are engaged in elucidating the molecular pathophysiology underlying stretch mark formation. This knowledge could open the door to rational treatment choices in the future.

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