The SURTAVI clinical trial is testing the use of the Medtronic CoreValve on aortic stenosis patients at moderate risk for surgery.
An option for patients with severe aortic stenosis
issue 18 | spring/summer 2013
Earlier this year, U-M expanded its use and testing of transcatheter aortic valve replacement (TAVR) procedures with the launch of the Medtronic CoreValve SURTAVI clinical trial, which includes patients with symptomatic severe aortic stenosis who are at moderate risk for aortic valve surgery.
The emergence of TAVR procedures in the U.S. is providing new hope for patients at high risk for surgery or who are not surgical candidates, half of whom could die within two years without treatment. The procedures allow access to the diseased aortic valve using a catheter, usually inserted through an artery in the leg, rather than through open heart surgery. The new valve is placed in the beating heart over the existing valve. Patients are home from the hospital in three to five days.
The SURTAVI trial is the latest TAVR trial to be taken on by the cardiac surgeons and interventional cardiologists at the newly renamed University of Michigan Samuel and Jean Frankel Cardiovascular Center. The U-M TAVR team is also participating in the Medtronic CoreValve TAVR trial for patients at high risk or who are ineligible for surgery, and is using the Edwards SAPIEN transcatheter heart valve, which is FDA-approved for use in high-risk or non-surgical patients.
The U-M TAVR program is led by Stanley J. Chetcuti, M.D., Eric J. Topol Collegiate Professor of Cardiovascular Medicine, Internal Med-Cardiology; P. Michael Grossman, M.D., professor of Cardiovascular Medicine, Internal Med-Cardiology; G. Michael Deeb, M.D., Herbert Sloan Collegiate Professor of Cardiac Surgery; and Himanshu J. Patel, M.D., associate professor of Cardiac Surgery.
The U-M Frankel Cardiovascular Center performs more than 600 surgical aortic valve procedures a year; more than any other Michigan hospital. And for TAVR, our team has the highest volume of implants in the state and is also among the top in the country in terms of volume.