This information is approved and/or reviewed by U-M Health System providers but it is not a tool for self-diagnosis or a substitute for medical treatment. You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition.| Complete disclaimer

Sulfate oral laxative preparation: Suprep

If you have kidney disease, you should NOT use this preparation. Also, if you take medicines for blood pressure or heart disease (ACE inhibitors or angiotensin receptor blockers), diuretics (water pills), or certain arthritis medicines (NSAIDs) you should not use this type of preparation unless instructed to do so by your health care provider.

You will need a prescription for Suprep. Start the prep the evening before your colonoscopy. Plan to be near a bathroom for the rest of the evening. Your bowels may begin to move in about 30–60 minutes. Feelings of nausea and bloating are common and resolve with time. An A&D-type ointment applied to the rectal area can help with any irritation. The goal is for your stool to be clear or light yellow water. It is very important that you drink all of the water as instructed below; complications can occur if you do not.

The evening before the colonoscopy:

___ Pour one (1) bottle of Suprep into the sixteen (16) ounce container provided and fill to the line with drinking water. Drink all the solution.

___ Over the next two (2) hours, drink two (2) more of the container provided filled with water (or approved clear liquid). Save the container for the next day.

 

The morning of the colonoscopy:

___ Starting four (4) hours before you need to leave home, pour one (1) bottle of Suprep into the container provided and fill to the line with drinking water. Drink all of the solution.

___ Over the next two (2) hours, drink two (2) more of the container provided filled with water (or approved clear liquid). See the colonoscopy booklet for allowed liquids. You must finish the last container of clear liquid at least two (2) hours before your scheduled appointment time.

 
Information provided by the University of Michigan Health System, Internal Medicine Gastroenterology Clinics and Medical Procedures Unit. February 2011.