This information is approved and/or reviewed by U-M Health System providers but it is not a tool for self-diagnosis or a substitute for medical treatment. You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition.| Complete disclaimer
Secretin Stimulation Test (SST)
What is a Secretin Stimulation Test? Image
This test measures the ability of the pancreas to respond to a hormone called secretin. The small intestine produces Secretin when partially digested food has moved into the intestine from the stomach. Your doctor has requested this test, which will indicate the response of Gastrin, a naturally occurring hormone, to the injection of a medication called Secretin. During the test, a small tube (a catheter) will be placed in your arm to take blood samples and infuse the medication Secretin. The stimulation test lasts approximately two hours and is performed in the GI Physiology Laboratory in the Medical Procedures Unit.
How do I prepare for this test?
A Gastric Acid Study is routinely performed before this test will be ordered. Please consult with your ordering physician and health insurance company to insure coverage.
Please consult your healthcare insurance company before scheduling the test. Not all insurance companies cover the costs for this test. If we do not have insurance coverage authorization prior to the test you will be responsible for payment
Please follow these guidelines for a successful test:
- Discontinue using Nexium, Protonox, Aciphex, Prilosec and Prevacid seven days before this test.
- Do not take Tagamet, Zantac, Pepcid or Axid within 24 hours of the test.
- If you have diabetes, please take ½ of morning dose of Insulin.
- Do not have anything to eat or drink after 10 pm the night before your test. Having an empty stomach will reduce risk of complications.
- Do not smoke and wear comfortable clothing when you come in for the test.
Total test time is 2 ½ hours.
If you are unable to keep your appointment or have questions about the test or medications, please call the GI Physiology Lab in the MPU at 734-936-9250, option 2.
U-M Health System Related Sites:
Department of Internal Medicine Division of Gastroenterology
Other Related Web Sites:
Your Digestive System and How it Works
Information provided by GI Physiology Laboratory staff, February 2011