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Chronic Multisymptom Illness

Chronic Multisymptom Illness, also known as CMI, include regional and organ-specific symptoms and syndromes that often accompany fibromyalgia.

Researchers define chronic multisymptom illness as the presence, for 6 months or longer, of one or more symptoms from at least two of the following clusters: general fatigue, mood and cognitive abnormalities, and musculoskeletal pain.

CMI is very difficult to diagnose because there is an overlap of different syndromes such as:

The graphic below shows the overlap of different syndromes.


The chart below shows the different symptoms and syndromes that can be included in chronic multi-symptom illnesses.



Information provided by UMHS Chronic Pain and Fatigue Research Center, May, 2007