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U-M Health SystemThis information is approved and/or reviewed by U-M Health System providers but it is not a tool for self-diagnosis or a substitute for medical treatment. You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition.

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Excision Biopsy

What is an excision biopsy?

An excision biopsy is a procedure for complete removal of a lump or abnormal area from the skin or other part of the body. The tissue is then sent to a lab for tests.

When is it used?

An excision biopsy is done to look for cancer, infection, and inflammation. It is often used to confirm a diagnosis. In some cases it may also be done to treat a problem, such as removal of a small skin cancer.

How do I prepare for an excision biopsy?

Your health care provider will tell you how to prepare for the procedure. Ask your provider when and how you will be informed of the results.

What happens during the procedure?

You will be given a local anesthetic. The anesthetic numbs just the skin and tissues that will be removed. You may also be given a sedative. A sedative helps you relax and may put you to sleep.

The doctor will cut into or through the skin and remove the abnormal tissue. The doctor will then close the cut with stitches. The tissue is sent to the lab for tests.

What happens after the procedure?

Keep the area of the cut dry. Do not put lotion, medicine, or ointment on it unless instructed to do so by your health care provider. You will be instructed about any other wound care and when to return for suture removal. Unless your provider tells you otherwise, there is nothing else you need to do.

The results of the lab tests will be available in 1 to 3 days or longer, depending on the type of tests that are done. Ask your provider when to call for results of the biopsy.

What are the benefits of this procedure?

The procedure helps in diagnosis of cancer, infection, and inflammation. You and your health care provider can then decide on a treatment plan.

What are the risks associated with this procedure?

  • The local anesthetic may not numb the area quite enough and you may feel some minor discomfort. If this happens, more anesthetic will be used. Also, in rare cases, you may have an allergic reaction to the drug used in this type of anesthesia.
  • You may have bruising around the biopsy site.
  • You may have infection or bleeding.

You should ask your health care provider how these risks apply to you.

When should I call my health care provider?

Call your right away if:

  • You have any change or worsening of pain or symptoms.
  • You have any unusual drainage from the biopsy site, including bloody drainage.
  • The biopsy site becomes red and warm.
  • You develop a fever.

Call your provider during office hours if:

  • You have questions about the procedure or its result.
  • You want to make another appointment.
Developed by Phyllis G. Cooper, RN, MN, and McKesson Provider Technologies.
Published by McKesson Provider Technologies.
Last modified: 2004-11-01
Last reviewed: 2004-10-29
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
Copyright © 2005 McKesson Corporation and/or one of its subsidiaries. All Rights Reserved.
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